Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.76 |
| ▸ | HTT | P42858 | 4/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767736 | 0.87 | IDO1 (1.00) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL3770841 | 0.87 | IDO1 (0.51) | IDO1HTTCYP1A2HPGDLMNA | |
| SCHEMBL20932624 | 0.76 | MAPT (0.56) | IDO1HTTCYP1A2HPGDLMNA | |
| SCHEMBL22275663 | 0.76 | IDO1 (0.77) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| Bromide SCHEMBL22262971 | 0.75 | IDO1 (0.78) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL13007592 | 0.75 | IDO1 (0.75) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL13256328 | 0.72 | IDO1 (0.71) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL13256341 | 0.71 | IDO1 (0.69) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL15457410 | 0.71 | IDO1 (0.70) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| Hydrochloric Acid SCHEMBL3421387 | 0.70 | IDO1 (0.68) | IDO1HTTCYP1A2CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | disclosed |