Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256346 | 0.88 | IDO1 (0.53) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL13256337 | 0.85 | IDO1 (0.50) | IDO1HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3767736 | 0.82 | IDO1 (1.00) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL13283510 | 0.82 | IDO1 (0.47) | IDO1HTTCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL14531235 | 0.81 | IDO1 (0.64) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL13256342 | 0.80 | CYP1A2 (0.47) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL15457410 | 0.76 | IDO1 (0.70) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL13256320 | 0.75 | CRHBP (0.43) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL3421387 | 0.75 | IDO1 (0.68) | IDO1HTTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL9843530 | 0.74 | HTT (0.50) | IDO1HTTMAPK1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010025448-A2 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | MKI67, RB1, RAF1 | IDO1 4276/4885HTT 3856/4885CYP1A2 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.