SCHEMBL5318376

SCHEMBL5318376

COC(=O)c1cc(NCCCOc2ccc(F)cc2)ccc1OC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GCGR P47871 1/20 0.42
PPARA Q07869 1/20 0.40
SCN9A Q15858 1/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
EGFR P00533 1/20 0.39
PTPN1 P18031 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5317330 0.97 FAAH (0.44) FAAHKMT2AMEN1NPC1MAPT
Methoxymethane SCHEMBL5318378 0.90 PPARA (0.47) FAAHKMT2AMEN1NPC1MAPT
SCHEMBL5317025 0.90 L3MBTL1 (0.47) KMT2AMEN1NPC1MAPTRAB9A
SCHEMBL5319097 0.88 KMT2A (0.42) KMT2AMEN1NPC1MAPTRAB9A
SCHEMBL5317740 0.88 MAPT (0.41) KMT2AMEN1MAPTSMN1; SMN2L3MBTL1
Methoxymethane SCHEMBL5317331 0.87 PPARA (0.47) FAAHKMT2AMEN1NPC1MAPT
SCHEMBL5317703 0.87 KMT2A (0.44) KMT2AMEN1NPC1MAPTL3MBTL1
SCHEMBL5317341 0.85 MAPT (0.49) FAAHKMT2AMEN1NPC1MAPT
SCHEMBL5321024 0.85 KDM4E (0.42) KMT2AMEN1MAPTSMN1; SMN2PPARA
SCHEMBL5318084 0.82 KMT2A (0.55) KMT2AMEN1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007119984-A1 SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM NEUROTECH CO., LTD. (KR) 2007-10-25 WO disclosed