Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424942 | 0.80 | L3MBTL1 (0.50) | PTK2L3MBTL1KDM4EHSD17B10NSD2 | |
| SCHEMBL27794571 | 0.80 | L3MBTL1 (0.50) | PTK2L3MBTL1KDM4EHSD17B10NSD2 | |
| SCHEMBL25210378 | 0.79 | MAPT (0.50) | KDM4ESORT1ALDH1A1TP53NNMT | |
| SCHEMBL7029088 | 0.79 | PTK2 (0.54) | PTK2L3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL30380776 | 0.79 | GSK3B (0.44) | SORT1CHEK1AURKAFLT4KDR | |
| SCHEMBL20031484 | 0.78 | PTK2 (0.53) | PTK2L3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL20605223 | 0.78 | GABRP (0.54) | PTK2L3MBTL1KDM4EHSD17B10NSD2 | |
| SCHEMBL23610778 | 0.78 | PTK2 (0.53) | PTK2L3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL25118045 | 0.77 | PTK2 (0.51) | PTK2L3MBTL1KDM4EJAK2JAK1 | |
| SCHEMBL31493083 | 0.76 | PTK2 (0.54) | PTK2L3MBTL1KDM4EJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |