Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339310 | 0.91 | CES2 (0.48) | GSK3BCES2CES1ALOX15TSHR | |
| SCHEMBL5319603 | 0.84 | KMT2A (0.53) | GSK3BCES2CES1ALOX15TSHR | |
| SCHEMBL5334151 | 0.84 | KMT2A (0.53) | GSK3BCES2CES1ALOX15TSHR | |
| SCHEMBL10392108 | 0.83 | MDM2 (0.47) | CES2CES1MDM2 | |
| SCHEMBL1481451 | 0.83 | CES2 (0.56) | CES2CES1TSHRMDM2KMT2A | |
| SCHEMBL13178294 | 0.82 | GSK3B (0.60) | GSK3BCES2CES1TPMTCA1 | |
| SCHEMBL4016467 | 0.82 | CES2 (0.52) | CES2CES1ALOX15TSHRKMT2A | |
| SCHEMBL627839 | 0.82 | CES2 (0.53) | CES2CES1ALOX15TSHRKMT2A | |
| SCHEMBL20429583 | 0.81 | GSK3B (0.42) | GSK3BCES2CES1ALOX15TSHR | |
| SCHEMBL7144679 | 0.79 | CYP19A1 (0.48) | GSK3BCES2CES1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |