Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337820 | 0.79 | MEN1 (0.63) | LMNATSHRCYP2C9BLMPPARA | |
| SCHEMBL4335866 | 0.74 | NQO1 (0.52) | LMNATSHRCYP2C9BLMPPARA | |
| SCHEMBL125543 | 0.72 | ALDH1A3 (0.64) | LMNATSHRKMT2AMEN1POLB | |
| SCHEMBL6427362 | 0.71 | LMNA (0.59) | LMNATSHRCYP2C9BLMPPARA | |
| SCHEMBL27954207 | 0.71 | LMNA (0.48) | LMNATSHRCYP2C9BLMPPARA | |
| SCHEMBL3326226 | 0.71 | LMNA (0.46) | LMNATSHRCYP2C9BLMPPARA | |
| SCHEMBL17082886 | 0.69 | TSHR (0.46) | TSHRKMT2AMEN1RAB9APOLB | |
| SCHEMBL14446350 | 0.69 | TSHR (0.54) | TSHRKMT2AMEN1RAB9APOLB | |
| SCHEMBL11691717 | 0.68 | ALDH1A3 (0.45) | LMNATSHRKMT2AMEN1POLB | |
| SCHEMBL4322138 | 0.68 | ALDH1A3 (0.41) | TSHRKMT2APOLBALDH1A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100161-A1 | METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-07 | — | — | WO | disclosed |