Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.77 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452488 | 1.00 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2456200 | 1.00 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2456196 | 1.00 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2452486 | 1.00 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL6017557 | 0.91 | ADRB2 (0.73) | ADRB2CHRM3ADRB3 | |
| SCHEMBL6507345 | 0.89 | ADRB2 (0.61) | ADRB2CHRM3ADRB3 | |
| SCHEMBL6017601 | 0.88 | ADRB2 (0.75) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037075 | 0.87 | ADRB2 (1.00) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037072 | 0.87 | ADRB2 (1.00) | ADRB2CHRM3ADRB3 | |
| SCHEMBL12305639 | 0.86 | ADRB2 (0.80) | ADRB2CHRM3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708991-B1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2007-10-17 | — | — | EP | claimed |