Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456200 | 0.88 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5318817 | 0.88 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2452486 | 0.88 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2456196 | 0.88 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2452488 | 0.88 | ADRB2 (0.77) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037072 | 0.86 | ADRB2 (1.00) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037075 | 0.86 | ADRB2 (1.00) | ADRB2CHRM3ADRB3 | |
| SCHEMBL6017557 | 0.86 | ADRB2 (0.73) | ADRB2CHRM3ADRB3 | |
| SCHEMBL12305639 | 0.86 | ADRB2 (0.80) | ADRB2CHRM3ADRB3 | |
| SCHEMBL14620429 | 0.86 | ADRB2 (0.80) | ADRB2CHRM3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708992-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2006-10-11 | — | — | EP | claimed |
| WO-2005080324-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2005-09-01 | — | — | WO | claimed |
| EP-1708992-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005080324-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |