Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798133 | 0.83 | MAPT (0.64) | MAPTSMN1; SMN2PLAUKDM4ESLC6A2 | |
| SCHEMBL4798142 | 0.83 | MAPT (0.64) | MAPTSMN1; SMN2PLAUKDM4EMEN1 | |
| SCHEMBL5322990 | 0.81 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2PLAUKDM4EMEN1 | |
| SCHEMBL28286591 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2ACHEPLAUKDM4E | |
| SCHEMBL5316585 | 0.74 | L3MBTL1 (0.51) | MAPTSMN1; SMN2ACHEKDM4ESLC6A2 | |
| SCHEMBL14951105 | 0.73 | KDM4E (0.48) | MAPTSMN1; SMN2ACHEKDM4EALDH1A1 | |
| SCHEMBL171894 | 0.73 | KDM4E (0.62) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL4796598 | 0.72 | KMT2A (0.49) | MAPTSMN1; SMN2PLAUKDM4EMEN1 | |
| SCHEMBL4796604 | 0.72 | KMT2A (0.49) | MAPTSMN1; SMN2PLAUKDM4EMEN1 | |
| SCHEMBL29403877 | 0.71 | ACHE (1.00) | MAPTSMN1; SMN2ACHEKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |