SCHEMBL5319231

SCHEMBL5319231

Cc1cc(F)c(NC(=O)C(C)C)cc1C1CCN(Cc2ccc(S(=O)(=O)C(C)C)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.54
ADRA1A P35348 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322079 0.93 DRD2 (0.49) DRD2ADRA1A
SCHEMBL4615778 0.90 DRD2 (0.55) DRD2ADRA1A
SCHEMBL5347220 0.89 DRD2 (0.52) DRD2ADRA1A
SCHEMBL5324223 0.84 DRD2 (0.66) DRD2ADRA1A
SCHEMBL4616577 0.83 DRD2 (0.55) DRD2ADRA1A
SCHEMBL5319226 0.79 DRD2 (0.46) DRD2ADRA1A
SCHEMBL14396922 0.76 DRD2 (0.53) DRD2ADRA1A
SCHEMBL14396933 0.76 DRD2 (0.51) DRD2ADRA1A
SCHEMBL5321322 0.76 DRD2 (0.44) DRD2ADRA1A
SCHEMBL4617822 0.75 DRD2 (0.68) DRD2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007114902-A2 ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS H.LUNDBECK A/S (DK) 2007-10-11 WO claimed
WO-2007114902-A2 ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS H.LUNDBECK A/S (DK) 2007-10-11 WO disclosed