Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319231 | 0.89 | DRD2 (0.54) | DRD2ADRA1A | |
| SCHEMBL4615778 | 0.87 | DRD2 (0.55) | DRD2ADRA1A | |
| SCHEMBL5324228 | 0.85 | DRD2 (0.63) | DRD2ADRA1AALDH1A1MAPK1 | |
| SCHEMBL5322079 | 0.81 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL4616577 | 0.81 | DRD2 (0.55) | DRD2ADRA1A | |
| SCHEMBL5319227 | 0.80 | DRD2 (0.44) | DRD2ADRA1AALDH1A1MAPK1 | |
| SCHEMBL5357569 | 0.76 | DRD2 (0.64) | DRD2ADRA1A | |
| SCHEMBL5319800 | 0.75 | GAA (0.42) | DRD2ADRA1AALDH1A1 | |
| SCHEMBL14396551 | 0.74 | DRD2 (0.47) | DRD2ADRA1A | |
| SCHEMBL5321967 | 0.74 | GAA (0.41) | DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114902-A2 | ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS | H.LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |