Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004879 | 0.81 | KDM4E (0.39) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL30445223 | 0.81 | KDM4E (0.39) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL29004881 | 0.81 | KDM4E (0.39) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL2019739 | 0.76 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL13173717 | 0.76 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL5324640 | 0.72 | EPHX2 (0.51) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL3826438 | 0.72 | EPHX2 (0.44) | KDM4EALDH1A1CHRM2OPRM1DDB1 | |
| SCHEMBL13558674 | 0.72 | EPHX2 (0.51) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL13173722 | 0.70 | DDB1 (0.41) | KDM4EHTTALDH1A1CHRM2OPRM1 | |
| SCHEMBL15436465 | 0.70 | DDB1 (0.41) | KDM4EHTTALDH1A1CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114125-A1 | PROCESS FOR PRODUCTION OF HYDROXYLATED ADAMANTANE USING MICROORGANISM | SHIONOGI & CO., LTD. (JP) | 2007-10-11 | — | — | WO | disclosed |