Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 4/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895300 | 0.73 | CA12 (0.38) | CA12CA1CA9ALDH1A1MMP1 | |
| SCHEMBL7770548 | 0.72 | CA12 (0.33) | CA12CA1CA9ALDH1A1CA2 | |
| SCHEMBL740657 | 0.72 | GPR84 (0.39) | ALDH1A1PPARGPPARDPPARATSHR | |
| SCHEMBL28083520 | 0.72 | GPR84 (0.39) | ALDH1A1PPARGPPARDPPARATSHR | |
| SCHEMBL28308675 | 0.72 | GPR84 (0.39) | ALDH1A1PPARGPPARDPPARATSHR | |
| SCHEMBL9340160 | 0.72 | AKR1B1 (0.35) | CA12CA1CA9ALDH1A1KDM5A | |
| SCHEMBL27921659 | 0.71 | CA12 (0.38) | CA12CA1CA9ALDH1A1MMP1 | |
| SCHEMBL20521655 | 0.71 | GRIK1 (0.36) | ALDH1A1PPARGPPARDPPARATSHR | |
| SCHEMBL6323038 | 0.71 | GPR84 (0.38) | ALDH1A1PPARGPPARDPPARATSHR | |
| SCHEMBL28674228 | 0.71 | GPR84 (0.38) | ALDH1A1PPARGPPARDPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085933-A2 | PROCESS FOR THE PREPARATION OF N-[1-(S)-ETHOXYCARBONYL-1-BUTYL]-(S)-ALANINE-DMT COMPLEX AND ITS USE IN THE PREPARATION OF PERINDOPRIL | GLENMARK PHARMACEUTICALS LIMITED (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2005108365-A1 | PROCESSES FOR THE PREPARATION OF ALPHA POLYMORPH OF PERINDOPRIL ERBUMINE | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-11-17 | — | — | WO | disclosed |
| US-20050250706-A1 | Processes for the preparation of alpha polymorph of perindopril erbumine | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250706-A1 | Processes for the preparation of alpha polymorph of perindopril erbumine | REN, VKORC1, VKORC1L1 | CA12 4558/4885CA1 4206/4885CA9 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.