Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321942 | 0.88 | MAPT (0.43) | L3MBTL1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL11261335 | 0.85 | LDHA (0.49) | LDHAMAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL5319860 | 0.80 | TDP1 (0.59) | LDHAL3MBTL1TDP1KDM4EMAPT | |
| SCHEMBL2672698 | 0.80 | LDHA (0.67) | LDHAMAPTALDH1A1HSD17B10 | |
| SCHEMBL11294410 | 0.80 | PPARG (0.44) | FFAR1MAPTCA1CA2NFKB1 | |
| SCHEMBL11296428 | 0.76 | TDP1 (0.63) | L3MBTL1TDP1MAPTMEN1KMT2A | |
| SCHEMBL7236478 | 0.74 | MTNR1A (0.49) | L3MBTL1TDP1ALDH1A1TSHRMAPK1 | |
| SCHEMBL17432930 | 0.74 | LDHA (0.53) | LDHAL3MBTL1TDP1FFAR1ATM | |
| SCHEMBL11290775 | 0.73 | MEN1 (0.59) | L3MBTL1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL11294287 | 0.73 | TDP1 (0.58) | L3MBTL1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096261-A2 | PROCESS FOR THE PREPARATION OF DIOXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-30 | — | — | WO | disclosed |
| US-20070197615-A1 | Process for the preparation of the PPAR alpha agonist NS-220 | HOFFMANN-LA ROCHE INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197615-A1 | Process for the preparation of the PPAR alpha agonist NS-220 | PPARD, PPARA, PPARG | LDHA 3259/4885L3MBTL1 4870/4885TDP1 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.