Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 6/20 | 0.76 |
| ▸ | FLT4 | P35916 | 6/20 | 0.76 |
| ▸ | KDR | P35968 | 6/20 | 0.76 |
| ▸ | VCP | P55072 | 3/20 | 0.61 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 9/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464876 | 0.89 | FLT1 (0.77) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL5480372 | 0.88 | FLT1 (0.69) | FLT1FLT4KDRVCPSIRT7 | |
| SCHEMBL5469587 | 0.88 | KDR (0.76) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL5480404 | 0.87 | KDR (0.97) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL5476166 | 0.86 | FLT1 (0.66) | FLT1FLT4KDRVCPSIRT7 | |
| SCHEMBL5319705 | 0.83 | VCP (0.69) | FLT1FLT4KDRVCPSIRT7 | |
| SCHEMBL5469678 | 0.82 | FLT1 (0.68) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL5477700 | 0.81 | KDR (0.76) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL14607281 | 0.78 | FLT1 (0.61) | FLT1FLT4KDRVCPIMPDH2 | |
| SCHEMBL5316678 | 0.77 | FLT1 (0.60) | FLT1FLT4KDRVCPIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |