Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189729 | 0.87 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4180696 | 0.77 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4184975 | 0.77 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13653096 | 0.76 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4178795 | 0.75 | HDAC1 (0.55) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28770269 | 0.74 | MAPT (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13653089 | 0.72 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4197650 | 0.72 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4193510 | 0.69 | HDAC1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2CDK4 | |
| SCHEMBL27632003 | 0.69 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802577-A1 | INDANE AMIDES WITH ANTIPROLIFERATIVE ACTIVITY | Bayer Pharmaceuticals Corporation (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006062580-A1 | INDANE AMIDES WITH ANTIPROLIFERATIVE ACTIVITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-06-15 | — | — | WO | disclosed |