Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319934 | 0.87 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4180696 | 0.86 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13653096 | 0.84 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4178795 | 0.84 | HDAC1 (0.55) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28770269 | 0.82 | MAPT (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4184975 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4193510 | 0.77 | HDAC1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2CDK4 | |
| SCHEMBL13653089 | 0.76 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4183216 | 0.76 | HDAC1 (0.46) | ACHECDK4CCND1NPC1RAB9A | |
| SCHEMBL4183294 | 0.76 | ACHE (0.48) | MEN1KMT2AMAPK1ACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247590-A1 | Indane amides | MKI67, PPIP5K2, CCNA1 | MEN1 612/4885KMT2A 1662/4885ALDH1A1 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.