Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814744 | 0.90 | NPC1 (0.73) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL3563966 | 0.86 | NPC1 (0.71) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6814208 | 0.84 | KMT2A (0.77) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6814432 | 0.83 | NPC1 (0.67) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6810726 | 0.83 | NPC1 (0.67) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL31408180 | 0.82 | L3MBTL1 (0.52) | NPC1RAB9AL3MBTL1HSP90AA1KMT2A | |
| SCHEMBL2090871 | 0.82 | NPC1 (0.60) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6810983 | 0.81 | NPC1 (0.74) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6810725 | 0.81 | NPC1 (0.74) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 | |
| SCHEMBL6819029 | 0.81 | NPC1 (0.64) | NPC1RAB9AL3MBTL1HSP90AA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089455-A1 | FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |