Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
| ▸ | GRK6 | P43250 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.56 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21594667 | 0.87 | NPC1 (0.51) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6814744 | 0.87 | NPC1 (0.73) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL18263632 | 0.87 | NPC1 (0.60) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2090866 | 0.85 | NPC1 (0.59) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7498200 | 0.85 | L3MBTL1 (0.59) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2093974 | 0.84 | NPC1 (0.52) | NPC1RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL151035 | 0.84 | ALDH1A1 (0.60) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6441147 | 0.84 | HTT (0.73) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL23084508 | 0.84 | NPC1 (0.58) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL21594658 | 0.84 | NPC1 (0.58) | NPC1RAB9AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638888-B | Oxidation process for the production of 5- (alkoxycarbonyl) furan-2-carboxylic Acid (ACFC) | 伊士曼化工公司 | 2024-04-02 | — | — | CN | claimed |
| EP-3810584-A1 | AN OXIDATION PROCESS TO PRODUCE 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS(ACFC) | Eastman Chemical Company (US) | 2021-04-28 | — | — | EP | claimed |
| CN-112638888-A | Oxidation process for the production of 5- (alkoxycarbonyl) furan-2-carboxylic Acid (ACFC) | 伊士曼化工公司 | 2021-04-09 | — | — | CN | claimed |
| US-10941245-B2 | Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) | EASTMAN CHEMICAL COMPANY (US) | 2021-03-09 | — | — | US | claimed |
| US-20250223272-A1 | COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE | EASTMAN CHEMICAL COMPANY (US) | 2025-07-10 | — | — | US | disclosed |
| EP-4025567-B1 | EFFICIENT PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)-FURAN-2-CARBOXYLIC ACIDS | EASTMAN CHEM CO (US) | 2025-04-23 | — | — | EP | disclosed |
| EP-4508041-A1 | COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE | Eastman Chemical Company (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250026729-A1 | INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) | EASTMAN CHEMICAL COMPANY (US) | 2025-01-23 | — | — | US | disclosed |
| US-20240317698-A1 | MOTHER LIQUOR COMPOSITION GENERATED IN MCFC PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2024-09-26 | — | — | US | disclosed |
| US-20240270708-A1 | PURGE PROCESS FOR 5-(ALKOXYCARBONYL)FURAN-2-CARBOYLIC ACID (ACFC) | EASTMAN CHEMICAL COMPANY (US) | 2024-08-15 | — | — | US | disclosed |
| CN-114364662-B | Efficient process for producing 5- (alkoxycarbonyl) -furan-2-carboxylic acid | 伊士曼化工公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4380925-A1 | INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) | Eastman Chemical Company (US) | 2024-06-12 | — | — | EP | disclosed |
| US-10941245-B2 | Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) | EASTMAN CHEMICAL COMPANY (US) | 2021-03-09 | — | — | US | disclosed |
| US-10544118-B2 | Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) | EASTMAN CHEMICAL COMPANY (US) | 2020-01-28 | — | — | US | disclosed |
| US-10544118-B2 | Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) | EASTMAN CHEMICAL COMPANY (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190389846-A1 | PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME | EASTMAN CHEMICAL COMPANY (US) | 2019-12-26 | — | — | US | disclosed |
| US-20190389846-A1 | PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME | EASTMAN CHEMICAL COMPANY (US) | 2019-12-26 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941245-B2 | Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) | MCCC2, ACSL5, ACACB | NPC1 4184/4885RAB9A 3237/4885L3MBTL1 4346/4885 |
| US-20250223272-A1 | COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE | ACACA, ADCY10, MCCC2 | NPC1 1148/4885RAB9A 611/4885L3MBTL1 4267/4885 |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | NPC1 3130/4885RAB9A 3153/4885L3MBTL1 2575/4885 |
| US-20240317698-A1 | MOTHER LIQUOR COMPOSITION GENERATED IN MCFC PROCESS | MCCC2, MLEC, ACSL5 | NPC1 4025/4885RAB9A 3739/4885L3MBTL1 3050/4885 |
| US-20190389846-A1 | PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME | CA5B, ACSL5, CA5A | NPC1 3648/4885RAB9A 1785/4885L3MBTL1 4406/4885 |
| US-10544118-B2 | Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) | MCCC2, ACSL5, ACACB | NPC1 4141/4885RAB9A 3587/4885L3MBTL1 4030/4885 |
| US-20240270708-A1 | PURGE PROCESS FOR 5-(ALKOXYCARBONYL)FURAN-2-CARBOYLIC ACID (ACFC) | MCCC2, ACACB, ACACA | NPC1 3408/4885RAB9A 2235/4885L3MBTL1 4362/4885 |
| US-20250026729-A1 | INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) | MCCC2, RFC5, ACSL5 | NPC1 2043/4885RAB9A 999/4885L3MBTL1 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.