Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609972 | 0.81 | NQO2 (0.63) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL5324314 | 0.80 | NQO2 (0.57) | NQO2MTNR1ACA2HTR6CYP1A2 | |
| SCHEMBL13911250 | 0.79 | NQO2 (0.57) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL31078221 | 0.77 | NQO2 (0.54) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL5513121 | 0.77 | CA2 (0.57) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL497025 | 0.77 | NQO2 (0.54) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL6511791 | 0.77 | NQO2 (0.54) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL31300446 | 0.77 | NQO2 (0.54) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL65445 | 0.77 | NQO2 (0.54) | NQO2MTNR1ACA2CYP1A2CYP2C19 | |
| SCHEMBL14675837 | 0.77 | NQO2 (0.48) | NQO2MTNR1ACA2HTR6CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772327-B2 | Phenylpropionic acid derivative and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
| WO-2007108743-A2 | NOVEL QUINAZOLINES AS 5-HT6 MODULATORS II | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | NQO2 1695/4885MTNR1A 1523/4885CA2 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.