Bromide

Bromide

SCHEMBL5320181

Br.COC(C)OC.[Ni]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3473432 0.95
Bromide SCHEMBL7648010 0.95
Bromide SCHEMBL7643612 0.95
Hydrochloric Acid SCHEMBL4132474 0.91
Bromide SCHEMBL29145230 0.91
SCHEMBL5306546 0.91 LMNA (0.31)
SCHEMBL11615697 0.91
SCHEMBL1153 0.91
Water SCHEMBL5322619 0.86
Hydrogen Sulfide SCHEMBL20377930 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117477029-A Electrolyte containing bifunctional additive, preparation method and lithium-sulfur battery 南昌大学 2024-01-30 CN disclosed
EP-2758416-B1 NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING (US) 2018-05-09 EP disclosed
US-9545624-B2 Nickel containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2017-01-17 US disclosed
US-8871878-B2 Ethylene polymerization using discrete nickel(II) iminophosphonamide complexes THE UNIVERSITY OF AKRON (US) 2014-10-28 US disclosed
EP-2758416-A2 NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS Dow Corning Corporation (US) 2014-07-30 EP disclosed
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-07-03 US disclosed
US-20130123444-A1 ETHYLENE POLYMERIZATION USING DISCRETE NICKEL(II) IMINOPHOSPHONAMIDE COMPLEXES THE UNIVERSITY OF AKRON (US) 2013-05-16 US disclosed
WO-2013043785-A2 NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed
WO-2007109232-A2 ETHYLENE POLYMERIZATION USING DISCRETE NICKEL (II) IMINOPHOSPHONAMIDE COMPLEXES UNIVERSITY OF AKRON (US) 2007-09-27 WO disclosed
US-20060058178-A1 Aromatic compounds containing nitrogen and p- functionalized amines, the production thereof and their use in catalytic reactions DEGUSSA AG (DE) 2006-03-16 US disclosed