Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473432 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL3802580 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL6498284 | 0.91 | — | — | |
| Bromide SCHEMBL5320181 | 0.91 | — | — | |
| SCHEMBL11615697 | 0.91 | — | — | |
| SCHEMBL1153 | 0.91 | — | — | |
| SCHEMBL5306546 | 0.91 | LMNA (0.31) | — | |
| Water SCHEMBL5322619 | 0.86 | — | — | |
| Water SCHEMBL1269330 | 0.86 | — | — | |
| Bromide SCHEMBL7648010 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084841-A | Synthesis method of high-purity delta-lactone | 江西香海生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116354995-A | Boron-containing chiral allyl ester compound and high-stereoselectivity synthesis method | 武汉大学 | 2023-06-30 | — | — | CN | claimed |
| CN-111454150-B | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-111423299-B | Photochemical catalytic synthesis method of aryl olefin compound | 北京工商大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115772133-A | Preparation method of bis-ethylhexyloxyphenol methoxyphenyl triazine | 安徽英特美科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-115536572-A | Sulfonyl hydrazide compound and preparation method and application thereof | 中国科学技术大学 | 2022-12-30 | — | — | CN | claimed |
| CN-111423331-B | Photochemical catalytic synthesis method of aryl alkyl ether | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-111039822-B | Photochemical catalytic synthesis method of aromatic azo compound | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-114805170-A | Preparation method of novel silodosin chiral intermediate | 四川青木制药有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-110256205-B | Method for removing olefin protective group by nickel catalysis | 常熟理工学院 | 2022-02-11 | — | — | CN | claimed |
| CN-113666862-A | Method for preparing chiral 3-nitroindole compound by nickel-catalyzed asymmetric nitration reaction | 山东大学 | 2021-11-19 | — | — | CN | claimed |
| CN-109096149-B | Process for the preparation of beta-arylamines | 富兰克科技（深圳）股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-111454150-A | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2020-07-28 | — | — | CN | claimed |
| US-5221774-A | Catalyst system containing nickel chloride, phosphine compound zinc and fluorinated organoacid | PHILLIPS PETROLEUM COMPANY (US) | 1993-06-22 | — | — | US | claimed |
| US-12037324-B2 | Biarylmethyl heterocycles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118201921-A | Lactams as CBL-B inhibitors selective for C-CBL | 基因泰克公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024114704-A1 | NOVEL IRAK4 INHIBITOR, AND COMPOUND FOR INHIBITING AND DEGRADING IRAK4 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2024-06-06 | — | — | WO | disclosed |
| EP-1284258-A2 | Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-02-19 | — | — | EP | disclosed |
| US-5233115-A | Using nickel halide, phosphine, carboxylate compound followed by contact with alkali metal borohydride | PHILLIPS PETROLEUM COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5221774-A | Catalyst system containing nickel chloride, phosphine compound zinc and fluorinated organoacid | PHILLIPS PETROLEUM COMPANY (US) | 1993-06-22 | — | — | US | disclosed |