Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469900 | 0.83 | EPHX1 (0.43) | KMT2AL3MBTL1CTSSCTSKCACNA1B | |
| SCHEMBL4848668 | 0.82 | EPHX1 (0.40) | KMT2AL3MBTL1ACECTSSCTSK | |
| SCHEMBL4848663 | 0.82 | EPHX1 (0.40) | KMT2AL3MBTL1ACECTSSCTSK | |
| SCHEMBL16470240 | 0.79 | EPHX1 (0.42) | KMT2AL3MBTL1ACEAKT1CTSS | |
| SCHEMBL2485598 | 0.78 | MAPT (0.47) | KMT2AL3MBTL1ACEKLK5 | |
| Hydrochloric Acid SCHEMBL4182358 | 0.78 | KMT2A (0.46) | KMT2AL3MBTL1CA12CA1CA7 | |
| Hydrochloric Acid SCHEMBL4182350 | 0.78 | KMT2A (0.46) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL1147463 | 0.77 | CTSS (0.41) | KMT2AL3MBTL1ACECTSSCTSK | |
| SCHEMBL490642 | 0.77 | CTSS (0.41) | KMT2AL3MBTL1ACECTSSCTSK | |
| SCHEMBL490571 | 0.77 | AKT1 (0.41) | KMT2AL3MBTL1ACECTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |