Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.40 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320310 | 1.00 | ENPP2 (0.45) | ENPP2GUCY1A1GUCY1B1SLC22A12CYP1A2 | |
| SCHEMBL5318021 | 0.91 | ENPP2 (0.40) | ENPP2SLC22A12CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5318017 | 0.91 | ENPP2 (0.40) | ENPP2SLC22A12CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5317439 | 0.91 | CYP1A2 (0.46) | ENPP2SLC22A12CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5317442 | 0.91 | CYP1A2 (0.46) | ENPP2SLC22A12CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5320443 | 0.89 | ENPP2 (0.41) | ENPP2GUCY1A1GUCY1B1NPSR1CDK2 | |
| SCHEMBL5320446 | 0.89 | ENPP2 (0.41) | ENPP2GUCY1A1GUCY1B1NPSR1CDK2 | |
| SCHEMBL1050572 | 0.89 | ENPP2 (0.54) | ENPP2GUCY1A1GUCY1B1SLC22A12CYP1A2 | |
| SCHEMBL1050570 | 0.89 | ENPP2 (0.54) | ENPP2GUCY1A1GUCY1B1SLC22A12CYP1A2 | |
| SCHEMBL5319964 | 0.89 | ENPP2 (0.41) | ENPP2GUCY1A1GUCY1B1SLC22A12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |