Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320446 | 1.00 | ENPP2 (0.41) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5323812 | 0.91 | PPARG (0.39) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5323817 | 0.91 | PPARG (0.39) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5319875 | 0.91 | LMNA (0.42) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5319872 | 0.91 | LMNA (0.42) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5320079 | 0.90 | ENPP2 (0.38) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5320075 | 0.90 | ENPP2 (0.38) | ENPP2CDK2MEN1KMT2AMAPT | |
| SCHEMBL5319158 | 0.90 | ENPP2 (0.48) | ENPP2LMNAGUCY1A1GUCY1B1NPSR1 | |
| SCHEMBL5319156 | 0.90 | ENPP2 (0.48) | ENPP2LMNAGUCY1A1GUCY1B1NPSR1 | |
| SCHEMBL5320310 | 0.89 | ENPP2 (0.45) | ENPP2CDK2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |