Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.69 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SNCA | P37840 | 4/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320380 | 0.90 | PTH1R (0.57) | PTH1RAPPMAPTSNCACCKBR | |
| SCHEMBL5320618 | 0.90 | PTH1R (0.55) | PTH1RAPPMAPTSNCACCKBR | |
| SCHEMBL5324664 | 0.89 | PTH1R (0.58) | PTH1RMCHR1CCKBR | |
| SCHEMBL5321708 | 0.89 | PTH1R (0.56) | PTH1RMCHR1ALDH1A1 | |
| SCHEMBL5324938 | 0.88 | PTH1R (0.53) | PTH1RSCN2ACCKBR | |
| SCHEMBL5322971 | 0.87 | PTH1R (0.54) | PTH1RAPPMAPTSNCAMCHR1 | |
| SCHEMBL5325678 | 0.86 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5280948 | 0.86 | PTH1R (0.76) | PTH1RCCKBR | |
| SCHEMBL5322001 | 0.85 | PTH1R (0.57) | PTH1RCCKBR | |
| SCHEMBL5327910 | 0.85 | PTH1R (0.56) | PTH1RMAPTMCHR1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |