Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 15/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320662 | 0.88 | PTH1R (0.54) | PTH1RALDH1A1MAPT | |
| SCHEMBL5328105 | 0.88 | PTH1R (0.54) | PTH1RALDH1A1MAPT | |
| SCHEMBL5322320 | 0.85 | PTH1R (0.50) | PTH1RSMN1; SMN2MAPTGAA | |
| SCHEMBL5326447 | 0.84 | PTH1R (0.52) | PTH1R | |
| SCHEMBL5319870 | 0.79 | PTH1R (0.60) | PTH1RALDH1A1MAPT | |
| SCHEMBL5329302 | 0.78 | PTH1R (0.49) | PTH1R | |
| SCHEMBL5325632 | 0.76 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5320888 | 0.76 | PTH1R (0.60) | PTH1R | |
| SCHEMBL5326711 | 0.76 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5321102 | 0.76 | PTH1R (0.57) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |