Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 17/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321308 | 0.87 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5326346 | 0.87 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5328105 | 0.84 | PTH1R (0.54) | PTH1RKMT2A | |
| SCHEMBL5320662 | 0.84 | PTH1R (0.54) | PTH1RKMT2A | |
| SCHEMBL5319870 | 0.83 | PTH1R (0.60) | PTH1RKMT2A | |
| SCHEMBL5326447 | 0.80 | PTH1R (0.52) | PTH1R | |
| SCHEMBL5328008 | 0.79 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5320370 | 0.78 | PTH1R (0.48) | PTH1R | |
| SCHEMBL5322320 | 0.76 | PTH1R (0.50) | PTH1RKMT2A | |
| SCHEMBL5355993 | 0.73 | PTH1R (0.53) | PTH1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |