Diamide

Diamide

SCHEMBL5320404

CCOCC.CN(C)C(=O)N=NC(=O)N(C)C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
TSHR P16473 2/20 0.65
HSD17B10 Q99714 2/20 0.65
NFKB1 P19838 1/20 0.65
THPO P40225 1/20 0.65
MAPT P10636 1/20 0.65
APEX1 P27695 1/20 0.65
PMP22 Q01453 1/20 0.65
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diamide SCHEMBL1302348 0.81 ALDH1A1 (0.77) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL39340 0.81 TSHR (1.00) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL103289 0.81 TSHR (1.00) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL13680778 0.81 TSHR (1.00) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL2036888 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL1681704 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL29975194 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL8186446 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL1772314 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO
Diamide SCHEMBL3793192 0.78 TSHR (0.93) ALDH1A1TSHRHSD17B10NFKB1THPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8716214-B2 Compositions for the targetted release of fragrances and aromas OTC GMBH (DE) 2014-05-06 US disclosed
US-20120183591-A1 Surfactant Mixtures for Improving the Deposition of Active Substances and for Reducing the Skin Irritant Action OTC GMBH (DE) 2012-07-19 US disclosed
US-20070105746-A1 Compositions for the targetted release of fragrances and aromas IFAC GMBH & CO. KG (DE) 2007-05-10 US disclosed
US-20070081953-A1 Surfactant mixtures for improving the deposition of active substances and for reducing the skin irritant action IFAC GMBH & CO.KG (DE) 2007-04-12 US disclosed
US-20060257334-A1 Mssn dispersion and method for producing the same IFAC GMBH & CO.KG INSTITUT FUR ANGEWANDTE COLLOIDTECHNOLOGIE (DE) 2006-11-16 US disclosed
US-20060024248-A1 Composition and method employing membrane structured solid nanoparticles for enhanced delivery of oral care actives COMBE INCORPORATED (US) 2006-02-02 US disclosed