Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345839 | 0.87 | MAPT (0.61) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL5347074 | 0.84 | MAPT (0.50) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL5319270 | 0.81 | MAPT (0.47) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL8233362 | 0.76 | MAPT (0.49) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL24461941 | 0.76 | MAPT (0.49) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL27489242 | 0.76 | CYP2A6 (0.50) | MAPTTLR8GAA | |
| SCHEMBL4808663 | 0.73 | CYP2A6 (0.54) | ALDH1A1KDM4EMAPTPKMRAB9A | |
| SCHEMBL82549 | 0.71 | PTGS1 (0.62) | ALDH1A1KDM4EMAPTPKMRAB9A | |
| SCHEMBL5318961 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTPKMTLR8 | |
| SCHEMBL16220807 | 0.70 | MIF (0.62) | ALDH1A1RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |