Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347074 | 0.90 | MAPT (0.50) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL8233362 | 0.88 | MAPT (0.49) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL5320946 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL24461941 | 0.84 | MAPT (0.49) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL8034913 | 0.81 | TLR8 (0.56) | MAPTALDH1A1KDM4ETLR8ADORA1 | |
| SCHEMBL5319270 | 0.80 | MAPT (0.47) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL25432056 | 0.79 | ADORA2A (0.54) | MAPTALDH1A1KDM4EPKMADORA1 | |
| SCHEMBL82549 | 0.78 | PTGS1 (0.62) | MAPTALDH1A1KDM4EPKMNPC1 | |
| SCHEMBL8233628 | 0.78 | TLR8 (0.50) | MAPTALDH1A1KDM4EPKMTLR8 | |
| SCHEMBL5318961 | 0.78 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EPKMTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110396116-B | [ N, O ] bidentate nickel and palladium complex of ketone-imidazoline-2-imine ligand, and preparation method and application thereof | 东华大学 | 2020-07-28 | — | — | CN | disclosed |
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |