Methoxymethane

Methoxymethane

SCHEMBL5320997

CC(=O)Oc1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1C(=O)O.COC

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
L3MBTL1 Q9Y468 1/20 0.58
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAPT P10636 3/20 0.53
HPGD P15428 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 2/20 0.53
MAPK1 P28482 2/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 1/20 0.53
MCHR1 Q99705 3/20 0.52
BRD4 O60885 1/20 0.51
ACHE P22303 1/20 0.51
TP53 P04637 1/20 0.51
RAB9A P51151 1/20 0.51
MCHR2 Q969V1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL5316763 0.92 POLB (0.53) MEN1KMT2AL3MBTL1NPSR1MAPT
SCHEMBL5320993 0.90 MEN1 (0.66) MEN1KMT2AL3MBTL1CYP1A2CYP3A4
Methoxymethane SCHEMBL5318055 0.88 ALDH1A1 (0.58) MEN1KMT2AL3MBTL1MAPTHPGD
Methoxymethane SCHEMBL5317339 0.83 MRGPRX4 (0.49) MEN1KMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL5316761 0.82 MEN1 (0.54) MEN1KMT2AL3MBTL1NPSR1MAPT
SCHEMBL10859430 0.81 MEN1 (0.65) MEN1KMT2AL3MBTL1CYP1A2CYP3A4
Methoxymethane SCHEMBL5318958 0.81 FFAR1 (0.58) MEN1KMT2AMAPTHPGDSMN1; SMN2
Methoxymethane SCHEMBL5318086 0.80 KMT2A (0.54) MEN1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL10016463 0.79 MEN1 (1.00) MEN1KMT2AL3MBTL1CYP1A2CYP3A4
SCHEMBL27374650 0.79 MEN1 (0.84) MEN1KMT2AL3MBTL1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007119984-A1 SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM NEUROTECH CO., LTD. (KR) 2007-10-25 WO disclosed