Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329879 | 0.88 | IDO1 (0.46) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL5322731 | 0.81 | TAAR1 (0.39) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL28722124 | 0.76 | MAPT (0.52) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL5330083 | 0.74 | TAAR1 (0.38) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL4933877 | 0.74 | BCHE (0.53) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL4929684 | 0.73 | MAPT (0.50) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL1001310 | 0.70 | TAAR1 (0.62) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL14029834 | 0.69 | TAAR1 (0.56) | TAAR1ALDH1A1POLBIDO1MLKL | |
| SCHEMBL20281649 | 0.69 | GRIN2B (0.43) | TAAR1ALDH1A1POLBIDO1TSHR | |
| SCHEMBL8330903 | 0.68 | TAAR1 (0.68) | TAAR1ALDH1A1POLBIDO1MLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |