Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321876 | 0.74 | TAAR1 (0.48) | TAAR1ALDH1A1POLBTSHRLMNA | |
| SCHEMBL5326871 | 0.67 | GRM2 (0.53) | LMNADRD4NPC1PKMRAB9A | |
| SCHEMBL5329879 | 0.66 | IDO1 (0.46) | TAAR1ALDH1A1POLBTSHRLMNA | |
| SCHEMBL14029834 | 0.63 | TAAR1 (0.56) | TAAR1ALDH1A1POLBSMN1; SMN2IDO1 | |
| SCHEMBL3983437 | 0.62 | LMNA (0.44) | TAAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL1001310 | 0.62 | TAAR1 (0.62) | TAAR1ALDH1A1POLBSMN1; SMN2IDO1 | |
| SCHEMBL28722124 | 0.61 | MAPT (0.52) | TAAR1ALDH1A1POLBTSHRLMNA | |
| SCHEMBL14005055 | 0.61 | TAAR1 (0.54) | TAAR1ALDH1A1POLBSMN1; SMN2IDO1 | |
| Hydrochloric Acid SCHEMBL5845865 | 0.61 | TAAR1 (0.65) | TAAR1ALDH1A1POLBSMN1; SMN2IDO1 | |
| SCHEMBL5322731 | 0.61 | TAAR1 (0.39) | TAAR1ALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |