Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329879 | 0.81 | IDO1 (0.46) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL5321876 | 0.81 | TAAR1 (0.48) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL4929684 | 0.70 | MAPT (0.50) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL28722124 | 0.70 | MAPT (0.52) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL4933877 | 0.69 | BCHE (0.53) | TAAR1KMT2AMAPK1MAPTIDO1 | |
| SCHEMBL25638545 | 0.66 | TAAR1 (0.55) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL20281649 | 0.65 | GRIN2B (0.43) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL5322728 | 0.65 | GRM2 (0.51) | LMNA | |
| SCHEMBL6866040 | 0.65 | TAAR1 (0.45) | TAAR1KMT2AALPLMAPK1MAPT | |
| SCHEMBL707879 | 0.64 | BCHE (0.73) | POLBSMN1; SMN2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |