⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416450 | 0.93 | — | — | |
| Boric Acid SCHEMBL27935964 | 0.89 | ALDH1A1 (0.33) | — | |
| SCHEMBL31742249 | 0.88 | ALDH1A1 (0.37) | — | |
| SCHEMBL8017928 | 0.83 | — | — | |
| SCHEMBL7922644 | 0.83 | — | — | |
| SCHEMBL7922642 | 0.83 | — | — | |
| SCHEMBL7983058 | 0.83 | — | — | |
| SCHEMBL8763250 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL12299444 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL28520747 | 0.78 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895478-B2 | Degradable polymer compositions and uses thereof | ISP INVESTMENTS INC. (US) | 2014-11-25 | — | — | US | claimed |
| US-20120157352-A1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2012-06-21 | — | — | US | claimed |
| EP-2414456-A1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | Isp Investments Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010114761-A1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | ISP INVESTMENT INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2008032060-A1 | 4-BENZIMIDAZ0LYL-6-M0RPH0LIN0-2-PIPERAZINYLPYRIMIDINE DERIVATIVES AS P13K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| US-20240423937-A1 | METHODS OF TREATING PAIN AND USES THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2024-12-26 | — | — | US | disclosed |
| US-20240156765-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2024-05-16 | — | — | US | disclosed |
| US-20240041808-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2024-02-08 | — | — | US | disclosed |
| EP-4199905-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | Oculotherapy, LLC (US) | 2023-06-28 | — | — | EP | disclosed |
| CN-116322664-A | Method of neuroprotection and uses thereof | 欧库罗治疗有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023028490-A1 | METHODS OF TREATING PAIN AND USES THEREOF | OCULOTHERAPY, LLC (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022040622-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | OCULOTHERAPY, LLC (US) | 2022-02-24 | — | — | WO | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |
| EP-0229944-A2 | Novel tetrahydroisoquinoline derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-07-29 | — | — | EP | disclosed |
| EP-0208921-A2 | Hydroformylation of olefinic compounds in the presence of soluble cobalt salt catalysts and an organic nitrile promoter | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4612403-A | Hydroformylation of olefinic compounds in the presence of a cobalt catalyst and an organic nitrile promoter | HENKEL CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4219684-A | REACTION OF AN OLEFIN WITH CARBON MONOXIDE AND HYDROGEN | UOP INC. (US) | 1980-08-26 | — | — | US | disclosed |