⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922644 | 1.00 | — | — | |
| SCHEMBL11406750 | 0.83 | — | — | |
| SCHEMBL9175469 | 0.83 | — | — | |
| SCHEMBL532188 | 0.83 | — | — | |
| SCHEMBL10416450 | 0.83 | — | — | |
| SCHEMBL21373707 | 0.80 | — | — | |
| SCHEMBL21373708 | 0.80 | — | — | |
| Boric Acid SCHEMBL27935964 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL31742249 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL7377831 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269734-A | JAK inhibitors | 维玛兰生物科学公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3966209-A1 | JAK INHIBITORS | Vimalan Biosciences, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |
| US-11136329-B2 | JAK inhibitors | VIMALAN BIOSCIENCES, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200369669-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. | 2020-11-26 | — | — | US | disclosed |
| WO-2020227563-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| US-7179926-B2 | Aryloxyalkylamine NK-1/SSRI inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1011667-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1011667-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998055119-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |