Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669945 | 0.84 | MEN1 (0.57) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL346186 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL5322174 | 0.76 | MEN1 (0.50) | ALDH1A1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL9835059 | 0.74 | — | — | |
| SCHEMBL347612 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL2498447 | 0.69 | — | — | |
| SCHEMBL352734 | 0.69 | — | — | |
| SCHEMBL27543707 | 0.69 | TSHR (0.41) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL39635 | 0.67 | — | — | |
| SCHEMBL27741471 | 0.67 | TSHR (0.42) | ALDH1A1MEN1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |