Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615593 | 0.92 | DRD2 (0.66) | DRD2ADRA1A | |
| SCHEMBL5328378 | 0.91 | DRD2 (0.63) | DRD2ADRA1A | |
| SCHEMBL5324516 | 0.89 | DRD2 (0.57) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5394994 | 0.89 | DRD2 (0.46) | DRD2ADRA1A | |
| SCHEMBL4617207 | 0.85 | DRD2 (0.60) | DRD2ADRA1A | |
| SCHEMBL4615167 | 0.85 | DRD2 (0.64) | DRD2ADRA1A | |
| SCHEMBL4617822 | 0.84 | DRD2 (0.68) | DRD2ADRA1A | |
| SCHEMBL5321793 | 0.84 | DRD2 (0.56) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5322183 | 0.83 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL4617548 | 0.83 | DRD2 (0.61) | DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |