Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322187 | 0.91 | DRD2 (0.57) | DRD2ADRA1A | |
| SCHEMBL4617822 | 0.85 | DRD2 (0.68) | DRD2ADRA1A | |
| SCHEMBL5328372 | 0.84 | DRD2 (0.55) | DRD2ADRA1A | |
| SCHEMBL5324923 | 0.83 | DRD2 (0.44) | DRD2ADRA1ADRD4CA12CA1 | |
| SCHEMBL4615593 | 0.83 | DRD2 (0.66) | DRD2ADRA1A | |
| SCHEMBL4615167 | 0.81 | DRD2 (0.64) | DRD2ADRA1A | |
| SCHEMBL5321991 | 0.81 | DRD2 (0.56) | DRD2ADRA1AMEN1KMT2A | |
| SCHEMBL5324721 | 0.80 | DRD2 (0.56) | DRD2ADRA1AMEN1KMT2A | |
| SCHEMBL5324516 | 0.80 | DRD2 (0.57) | DRD2ADRA1A | |
| SCHEMBL5394994 | 0.80 | DRD2 (0.46) | DRD2ADRA1ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |