Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | WDR5 | P61964 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562032 | 0.88 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2MAPTTP53CA12 | |
| SCHEMBL5318770 | 0.86 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2MAPTTP53CA12 | |
| SCHEMBL5318686 | 0.86 | HDAC3 (0.75) | LMNASMN1; SMN2HDAC1 | |
| SCHEMBL5318027 | 0.85 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2MAPTTP53CA12 | |
| SCHEMBL7170776 | 0.85 | LMNA (0.74) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL3554413 | 0.84 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2MAPTTP53CA12 | |
| SCHEMBL27790788 | 0.83 | LMNA (0.71) | LMNASMN1; SMN2MAPTTP53CA12 | |
| SCHEMBL9323512 | 0.83 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL7175640 | 0.83 | LMNA (0.70) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL96248 | 0.82 | LMNA (0.70) | LMNASMN1; SMN2MAPTTP53CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067993-A1 | INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007067993-A1 | INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |