SCHEMBL532235

SCHEMBL532235

Cc1ccc(-c2ccc3[nH]c4ccc(-c5ccc(C)s5)cc4c3c2)s1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 2/20 0.52
HTR1B P28222 2/20 0.52
PGR P06401 1/20 0.43
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KIF11 P52732 4/20 0.39
ACHE P22303 1/20 0.39
TLR9 Q9NR96 4/20 0.37
TLR8 Q9NR97 4/20 0.37
TLR7 Q9NYK1 4/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712147 0.78 AHR (0.55) KDM4EHSD17B10ALDH1A1HPGDRAB9A
SCHEMBL18099805 0.77 PGR (0.45) HTR1DHTR1BPGRKDM4EHSD17B10
SCHEMBL9927249 0.75 APP (0.48) HTR1DHTR1BPGRKDM4EHSD17B10
SCHEMBL25450824 0.75 PGR (0.46) HTR1DHTR1BPGRHSD17B10ALDH1A1
SCHEMBL14302818 0.74 PGR (0.50) HTR1DHTR1BPGRHSD17B10ALDH1A1
SCHEMBL2608311 0.74 PGR (0.62) HTR1DHTR1BPGRKDM4EHSD17B10
SCHEMBL20078660 0.74 PGR (0.50) HTR1DHTR1BPGRKDM4EHSD17B10
SCHEMBL13183133 0.74 HTR1D (0.43) HTR1DHTR1BPGRMAPTCLK2
SCHEMBL12277731 0.73 PGR (0.57) HTR1DHTR1BPGRKDM4EHSD17B10
SCHEMBL18267878 0.73 PGR (0.42) HTR1DHTR1BPGRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416392-B1 Light emitting device and display unit RICOH CO LTD (JP) 2016-05-25 EP disclosed
US-9263682-B2 Light emitting device and display unit RICOH COMPANY, LTD. (JP) 2016-02-16 US disclosed
US-9206202-B2 Carbazole derivative and semiconductor nanocrystal RICOH COMPANY, LTD. (JP) 2015-12-08 US disclosed
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL RICOH COMPANY, LTD. (JP) 2013-01-31 US disclosed
US-20120032115-A1 LIGHT EMITTING DEVICE AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2416392-A2 Light emitting device and display unit Ricoh Company, Ltd. (JP) 2012-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL NAT1, AHR, ARSA HTR1D 138/4885HTR1B 256/4885PGR 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.