SCHEMBL9927249

SCHEMBL9927249

Cc1ccc(-c2ccc(-c3ccc(C)s3)cc2)s1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 9/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
PGR P06401 1/20 0.47
NPC1 O15118 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 1/20 0.46
GFER P55789 1/20 0.46
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
SLC6A7 Q99884 1/20 0.41
CNR1 P21554 1/20 0.40
ERN1 O75460 1/20 0.40
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13424304 0.97 APP (0.46) APPESR1ESR2PGRNPC1
SCHEMBL10300218 0.97 APP (0.46) APPESR1ESR2PGRNPC1
SCHEMBL13376691 0.95 APP (0.50) APPESR1ESR2PGRNPC1
SCHEMBL147842 0.92 HSD17B1 (0.44) APPESR1ESR2PGRNPC1
SCHEMBL15599289 0.90 HSD17B1 (0.43) APPESR1ESR2PGRNPC1
SCHEMBL12307014 0.90 APP (0.46) APPESR1ESR2PGRNPC1
SCHEMBL2723923 0.88 CNR1 (0.53) APPESR1ESR2PGRNPC1
SCHEMBL13885536 0.88 RAB9A (0.52) APPPGRNPC1ALDH1A1HSD17B10
SCHEMBL11896154 0.88 APP (0.70) APPESR1ESR2PGRNPC1
SCHEMBL10016215 0.88 APP (0.45) APPESR1ESR2PGRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2764034-B1 POLYMERS BASED ON BENZODIONES CLAP CO LTD (KR) 2023-08-30 EP disclosed
EP-2334714-B1 METHOD OF PHOTOCHEMICAL HYDROLYSIS-POLYCONDENSATION OF CROSS-LINKABLE CHROMOPHORES WITH STERIC HINDRANCE, CATALYSED BY A PHOTOGENERATED ACID, AND THE APPLICATIONS THEREOF CENTRE NAT RECH SCIENT (FR) 2020-11-25 EP disclosed
EP-2834286-B1 DIKETOPYRROLOPYRROLE POLYMERS AND SMALL MOLECULES BASF SE (DE) 2019-01-23 EP disclosed
US-10003024-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-06-19 US disclosed
US-10003024-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-06-19 US disclosed
EP-3258513-A1 ORGANIC SEMICONDUCTOR ELEMENT AND METHOD FOR PRODUCING SAME, COMPOUND, ORGANIC SEMICONDUCTOR COMPOSITION AND ORGANIC SEMICONDUCTOR FILM AND METHOD FOR PRODUCING SAME FUJIFILM Corporation (JP) 2017-12-20 EP disclosed
US-9748487-B2 Polymers based on naphthodiones BASF SE (DE) 2017-08-29 US disclosed
US-9748487-B2 Polymers based on naphthodiones BASF SE (DE) 2017-08-29 US disclosed
EP-2917304-B1 POLYMERS BASED ON NAPHTHODIONES BASF SE (DE) 2016-10-26 EP disclosed
US-9424998-B2 Dye, photoelectric conversion element using the same, photoelectrochemical cell, and method of producing dye FUJIFILM CORPORATION (JP) 2016-08-23 US disclosed
WO-2009144302-A1 SEMICONDUCTOR MATERIALS AND METHODS OF PREPARATION AND USE THEREOF BASF SE (DE) 2009-12-03 WO disclosed
US-20090247728-A1 COPOLYMERS OF INDENOFLUORENE AND THIOPHENE MERCK PATENT GMBH (DE) 2009-10-01 US disclosed
US-20090247728-A1 COPOLYMERS OF INDENOFLUORENE AND THIOPHENE MERCK PATENT GMBH (DE) 2009-10-01 US disclosed
US-20090184635-A1 POLYMER BLENDS AND THEIR USE IN ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184635-A1 POLYMER BLENDS AND THEIR USE IN ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090043052-A1 LIVING SYNTHESIS OF CONDUCTING POLYMERS INCLUDING REGIOREGULAR POLYMERS, POLYTHIOPHENES, AND BLOCK COPOLYMERS CARNEGIE MELLON UNIVERSITY 2009-02-12 US disclosed
US-7452958-B2 Living synthesis of conducting polymers including regioregular polymers, polythiophenes, and block copolymers CARNEGIE MELLON UNIVERSITY (US) 2008-11-18 US disclosed
US-20080188670-A1 1,4-Dithienylbenzene Derivative NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) 2008-08-07 US disclosed
WO-2008011953-A1 POLYMER BLENDS AND THEIR USE IN ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2008-01-31 WO disclosed
WO-2008009343-A1 COPOLYMERS OF INDENOFLUORENE AND THIOPHENE MERCK PATENT GMBH (DE) 2008-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188670-A1 1,4-Dithienylbenzene Derivative SLC22A4, SLC19A2, SLC22A1 APP 3936/4885ESR1 2772/4885ESR2 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.