Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16416742 | 0.87 | MAPT (0.49) | CYP2C19HIF1AKMT2AMAPTALDH1A1 | |
| SCHEMBL1670311 | 0.80 | CYP2C19 (0.46) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL3702043 | 0.80 | PPARG (0.46) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL6898466 | 0.80 | CYP2C19 (0.46) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL4298978 | 0.79 | LMNA (0.46) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL5040791 | 0.78 | MAPK1 (0.50) | CYP2C19HIF1AKMT2AMAPTALDH1A1 | |
| SCHEMBL3726527 | 0.76 | CYP2C19 (0.42) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL9245013 | 0.76 | CYP2C19 (0.42) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL3128240 | 0.76 | MAPT (0.50) | CYP2C19HIF1APPARGPPARAKMT2A | |
| SCHEMBL27663466 | 0.75 | TSHR (0.45) | CYP2C19HIF1APPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008156-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING A SUBSTITUTED PHENYLPROPIONIC ACID AS A FREE ACID AND AS TERT-BUTYL AMINE SALT THEREOF | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |