Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617774 | 0.92 | DRD2 (0.54) | DRD2ADRA1AMAPTLMNAMAPK1 | |
| SCHEMBL5319996 | 0.91 | DRD2 (0.52) | DRD2ADRA1AMAPTLMNAMEN1 | |
| SCHEMBL5324516 | 0.89 | DRD2 (0.57) | DRD2ADRA1A | |
| SCHEMBL5394994 | 0.89 | DRD2 (0.46) | DRD2ADRA1AL3MBTL1MAPTLMNA | |
| SCHEMBL5388497 | 0.88 | DRD2 (0.45) | DRD2ADRA1AL3MBTL1MAPTLMNA | |
| SCHEMBL5320292 | 0.84 | DRD2 (0.44) | DRD2ADRA1AMAPTLMNAMAPK1 | |
| SCHEMBL4616000 | 0.84 | DRD2 (0.49) | DRD2ADRA1AMAPTMAPK1MEN1 | |
| SCHEMBL5321793 | 0.83 | DRD2 (0.56) | DRD2ADRA1A | |
| SCHEMBL4617177 | 0.82 | DRD2 (0.54) | DRD2ADRA1AMAPTLMNAMAPK1 | |
| SCHEMBL5322375 | 0.81 | DRD2 (0.41) | DRD2ADRA1AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |