Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319993 | 0.90 | DRD2 (0.47) | DRD2ADRA1AOGAMAPTLRRK2 | |
| SCHEMBL5324511 | 0.90 | DRD2 (0.49) | DRD2ADRA1AOGAMEN1KMT2A | |
| SCHEMBL5394993 | 0.88 | CHRM2 (0.47) | DRD2ADRA1AOGAALDH1A1 | |
| SCHEMBL5388493 | 0.88 | DRD2 (0.40) | DRD2ADRA1AOGAACKR3OPRM1 | |
| SCHEMBL5320289 | 0.84 | DRD2 (0.40) | DRD2ADRA1AOGAMEN1KMT2A | |
| SCHEMBL4617774 | 0.83 | DRD2 (0.54) | DRD2ADRA1AACKR3MEN1MAPT | |
| SCHEMBL5320284 | 0.82 | DRD2 (0.46) | DRD2ADRA1AMEN1MAPTKMT2A | |
| SCHEMBL5327258 | 0.82 | DRD2 (0.46) | DRD2ADRA1AOGAALDH1A1 | |
| SCHEMBL5323016 | 0.81 | DRD2 (0.46) | DRD2ADRA1AMEN1MAPTKMT2A | |
| SCHEMBL5322376 | 0.81 | DRD2 (0.46) | DRD2ADRA1AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |