Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.67 |
| ▸ | TAS1R2 | Q8TE23 | 10/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322392 | 1.00 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2BRD4CREBBP | |
| SCHEMBL10226890 | 0.80 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL8919106 | 0.80 | BRD4 (0.53) | TAS1R3TAS1R1TAS1R2BRD4CREBBP | |
| SCHEMBL701799 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1P2RX7 | |
| SCHEMBL701854 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL701855 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL784603 | 0.78 | ALDH1A1 (0.50) | TAS1R3TAS1R1TAS1R2BRD4CREBBP | |
| SCHEMBL784602 | 0.78 | ALDH1A1 (0.50) | TAS1R3TAS1R1TAS1R2BRD4CREBBP | |
| SCHEMBL20860976 | 0.77 | TAS1R3 (0.93) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL27125516 | 0.77 | TRPV1 (0.50) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203142-A | Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers | SENOMYX INC (US) | 2008-06-18 | — | — | CN | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |