Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436067 | 0.84 | POLB (0.30) | — | |
| SCHEMBL6333420 | 0.83 | PDE10A (0.35) | — | |
| SCHEMBL5318680 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL5321153 | 0.79 | CCNA2 (0.39) | — | |
| SCHEMBL6336115 | 0.79 | CCNA2 (0.30) | — | |
| SCHEMBL6335653 | 0.77 | CCNA2 (0.39) | — | |
| SCHEMBL6344435 | 0.75 | EDNRA (0.31) | — | |
| SCHEMBL6345237 | 0.73 | LRRK2 (0.30) | — | |
| SCHEMBL5318252 | 0.72 | CNR2 (0.34) | — | |
| SCHEMBL5320750 | 0.72 | CCNA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089031-A1 | PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-09 | — | — | WO | disclosed |