SCHEMBL5318680

SCHEMBL5318680

COc1nc(C2CC2)nc(CC(C)C)c1Br

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322503 0.79 MTNR1A (0.31)
SCHEMBL6341144 0.76 TSHR (0.36) ALDH1A1
SCHEMBL11444512 0.72 PDE10A (0.33) ALDH1A1
SCHEMBL6340021 0.72 CNR2 (0.31)
SCHEMBL14435742 0.70 PDE10A (0.39)
SCHEMBL6336289 0.70 EDNRB (0.31)
SCHEMBL6335620 0.69 ADORA2A (0.38)
SCHEMBL6826635 0.68 PDE10A (0.35)
SCHEMBL24344999 0.67 PDE10A (0.50)
SCHEMBL14436067 0.66 POLB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007100831-A2 METHOD FOR POLYMER SYNTHESIS USING MICROFLUIDIC ENZYMATIC CASCADE TUFTS UNIVERSITY (US) 2007-09-07 WO disclosed
WO-2007089031-A1 PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-09 WO disclosed