SCHEMBL5322668

SCHEMBL5322668

CC(Cc1ccc(OC(C)(C)C(=O)O)cc1)NC(=O)c1cc(F)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.46
PPARA Q07869 11/20 0.44
PPARD Q03181 7/20 0.44
PPARG P37231 4/20 0.44
ACACB O00763 3/20 0.43
CNR2 P34972 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14399419 0.89 PPARA (0.42) CNR1PPARAPPARGACACBCNR2
SCHEMBL5327251 0.84 PPARD (0.49) CNR1PPARAPPARD
SCHEMBL5321703 0.83 CDK2 (0.47) PPARGACACB
SCHEMBL5321265 0.82 PPARA (0.44) CNR1PPARAPPARDPPARGACACB
SCHEMBL5326681 0.82 CNR1 (0.48) CNR1PPARAPPARDPPARGACACB
SCHEMBL5329478 0.82 PPARA (0.54) CNR1PPARAPPARDPPARG
SCHEMBL3685481 0.81 ACACB (0.61) CNR1PPARAPPARDPPARGACACB
SCHEMBL5325385 0.76 CTSS (0.48) CNR1PPARAPPARDPPARGACACB
SCHEMBL5321440 0.76 POLB (0.54) CNR1PPARAPPARGACACBCNR2
SCHEMBL5351942 0.76 PPARA (0.47) CNR1PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007118963-A2 SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF GENFIT (FR) 2007-10-25 WO claimed
WO-2007118963-A2 SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF GENFIT (FR) 2007-10-25 WO disclosed